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“text”: “Cold laser (super-pulsed) delivers very short, high-energy bursts of light that produce no heat in the tissue. The primary mechanism is photochemical — light is absorbed by cells to trigger biological responses. High-power Class IV lasers deliver continuous energy at higher average power, which creates thermal effects in the tissue. Both have clinical applications, but they work through different mechanisms.”
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“text”: “Both types are used clinically and both have established safety protocols. However, there are practical differences. Class IV lasers carry thermal risk if not moved continuously, require mandatory laser safety eyewear for the patient and all personnel, and typically need dedicated treatment rooms with door interlocks and warning signage. Super-pulsed Class 1M devices carry no burn risk, do not require protective eyewear at treatment distances, and have no special room requirements.”
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Comparison
Cold Laser vs Class IV Laser — What’s the Difference?
Two types of laser therapy. Two different mechanisms. Understanding the distinction may help you make a more informed decision about your care.
Not all laser therapy is the same
If you have been researching laser therapy, you have probably come across two very different types of devices being marketed under similar names. One is sometimes called “cold laser,” “low-level laser” or “photobiomodulation.” The other is called “Class IV laser” or “high-power laser therapy.” Both involve pointing a laser at the body. That is roughly where the similarities end.
The distinction matters because these two categories work through different physical mechanisms, carry different safety profiles, and have different bodies of published research behind them.
The confusion is understandable. Many clinics simply advertise “laser therapy” without specifying which type, which power levels, or which wavelengths. Some marketing implies that more power always means better results. The published evidence does not support that assumption.
How laser classifications work
Lasers are classified by their potential to cause harm, particularly to the eyes and skin:
- Class 1M — considered safe under all normal conditions of use. No burn risk. No mandatory eye protection at treatment distances. This is the classification of the super-pulsed device we use.
- Class 3B — moderate risk. Requires eye protection. Low average power (up to 500 mW). Many traditional cold laser therapy devices fall into this category.
- Class IV — highest classification. Capable of causing burns and retinal damage. Requires mandatory protective eyewear, dedicated treatment rooms, and continuous device movement during application. Average power ranges from 500 mW to 60+ W.
The classification is not about therapeutic effectiveness — it is about safety risk. A device can deliver therapeutic photon density without requiring the highest risk classification.
Individual responses to any laser therapy vary. This page provides general educational information, not clinical advice for your specific situation.
How super-pulsed cold laser works
Our super-pulsed laser uses a gallium arsenide (GaAs) semiconductor diode at 905 nm to deliver super-pulsed laser energy. Here is what that means in practical terms.
Short, powerful bursts — no heat
Each pulse lasts roughly 100 to 200 nanoseconds. During that pulse, peak power reaches 50,000 milliwatts (50 W). But because the pulse is so brief and the duty cycle is approximately 0.001%, the average power across the full cycle stays very low — around 7 to 12 milliwatts. The tissue absorbs the light energy during the pulse, then the long “off” period allows any thermal energy to dissipate completely.
The simplest analogy: a desk lamp left on continuously creates warmth. A camera flash delivers far more light in the instant it fires, but produces no heat because the burst is so brief.
Four wavelengths, sequenced
Our super-pulsed laser is not a single-wavelength device. It delivers four wavelengths simultaneously:
- 455 nm (blue) — targets superficial tissue, approximately 1 mm depth
- 660 nm (red) — interacts with tissue at 0.5 to 3 mm depth
- 875 nm (broadband infrared) — reaches 2 to 5 mm depth
- 905 nm (super-pulsed infrared) — the primary therapeutic wavelength, reaching deeper structures
Each wavelength is sequenced so that shallower wavelengths prepare the optical pathway for the deeper ones — a cascading effect.
Photochemical, not photothermal
The therapeutic mechanism is photon absorption by cytochrome c oxidase in the mitochondria — a photochemical reaction. This is the same fundamental mechanism described in the broader photobiomodulation research base. The key distinction is that super-pulsing delivers the necessary photon density for this reaction without generating clinically significant heat.
A 2015 study (Grandinetti et al.) tested the Multi-Radiance super-pulsed device at 10 J, 30 J and 50 J doses across all skin types and found no significant skin temperature increases at any dose (PMID: 25987340).
Individual responses to photobiomodulation vary. Not all patients will experience the same outcomes.
How Class IV (high-power) laser works
Class IV lasers operate at a fundamentally different power level. They deliver continuous-wave or near-continuous energy at average power outputs ranging from 500 milliwatts to over 60 watts. Common wavelengths include 808 nm, 980 nm and 1064 nm.
Thermal effect is inherent
Because the energy delivery is continuous rather than pulsed, Class IV lasers generate significant heat in tissue. This is not a side effect — it is part of the mechanism. Some proponents argue the thermal effect itself is therapeutic (increasing blood flow, relaxing tissue). Others see it as a limitation that must be managed.
Movement is mandatory
To prevent thermal injury, the practitioner must move the device continuously across the treatment area. Holding a Class IV laser stationary on the skin risks burning the tissue. This constant movement means the device spends less dwell time on any specific target point compared to a stationary application.
Safety requirements
Class IV devices require:
- Mandatory laser safety eyewear for the patient and all personnel in the room
- Dedicated treatment rooms with door interlocks and warning signage in many jurisdictions
- Continuous movement during application to prevent burns
- Restricted application areas (eyes, thyroid, gonads, over metal implants)
A different mechanism profile
While Class IV manufacturers also reference photobiomodulation, the combination of continuous high power and thermal effects means the mechanism is a mix of photothermal and photochemical, rather than purely photochemical. This distinction is clinically relevant because the published photobiomodulation dose recommendations from bodies like the World Association for Laser Therapy (WALT) specifically differentiate super-pulsed 904 nm dosing from continuous-wave dosing.
Class IV devices have clinical applications. This is not about one being “good” and the other “bad.” They are different tools with different risk profiles, different mechanisms and different evidence bases.
This section is provided for general education. It does not constitute clinical advice about any specific device or protocol.
Side-by-side comparison
| Feature | Super-Pulsed (our super-pulsed laser) | Class IV (High-Power) |
|---|---|---|
| Laser classification | Class 1M | Class IV |
| Average power output | ~7–12 mW | 500 mW to 60+ W |
| Peak pulse power | 50,000 mW (50 W) | Continuous (no pulsing in most devices) |
| Primary mechanism | Photochemical | Photothermal + photochemical |
| Thermal effect | Non-thermal — no measurable skin temperature increase (Grandinetti 2015) | Thermal — tissue heating is inherent |
| Penetration | Pulsed delivery shown to penetrate 2.7x deeper than continuous wave at same wavelength (Barbora 2021) | Higher power does not equal deeper penetration — 1064 nm advantage over 905 nm vanishes beyond 10 mm (Kaub & Schmitz 2023) |
| Treatment sensation | No sensation or mild tingling | Warmth; potential discomfort if held stationary |
| Eye protection | Not required at treatment distances (Class 1M) | Mandatory for patient and all personnel |
| Burn risk | None — can be held stationary on skin | Yes — must be moved continuously |
| Room requirements | No dedicated room, interlocks or signage required | Dedicated room, door interlocks and warning signage in many jurisdictions |
| Wavelengths | 455, 660, 875, 905 nm (four simultaneous) | Typically 808, 980 or 1064 nm (one or two) |
| 980 nm water absorption | Not used — avoids this issue | Common wavelength; significant water absorption converts energy to heat in superficial tissue |
| Published RCT base | Majority of 700+ PBM RCTs used Class 3B or super-pulsed parameters | Class IV-specific RCTs are fewer; evidence base still developing |
| Regulatory (Australia) | TGA-registered (Class IIa) | Varies by device |
| Portability | 250 g, cordless, rechargeable | Typically larger bench-top units with mains power |
This comparison is for general educational purposes. Both device categories have clinical applications and published research. Individual results vary regardless of device type.
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What the research suggests
Published research relevant to the super-pulsed vs continuous-wave distinction. All citations are verifiable on PubMed.
Pulsed wave penetrates deeper than continuous wave
Barbora et al. (2021) found that 808 nm pulsed-wave laser penetrated 2.7 times deeper into tissue than 808 nm continuous-wave at the same wavelength — suggesting that pulsing mechanism, not raw power, may be the primary determinant of penetration depth.
PMID: 33411831
Longer wavelength advantage is only superficial
Kaub and Schmitz (2023) found that 1064 nm showed only up to 5.9% higher transmittance than 905 nm in the upper 10 mm of tissue. Beyond 10 mm, “the difference vanished.” The clinical advantage of longer wavelengths commonly used in Class IV devices appears to be primarily superficial.
PMID: 37239026
Thermal safety: pulsed vs continuous
Chaki et al. (2025) computationally demonstrated that pulsed-wave delivery at 60 W peak with 10% duty cycle achieved a skin surface temperature of 42.5 °C (below the 43 °C safety threshold) while delivering approximately 4.2 J/cm² to deep muscle. Continuous-wave delivery at 30 W average power exceeded 76 °C at the skin surface.
PMID: 40384056
Biphasic dose response
Huang et al. (2009) established the biphasic dose response in photobiomodulation: low levels of light stimulate and support tissue repair, while excessive levels may be inhibitory. This has direct implications for high-power devices that risk overshooting the therapeutic window.
PMID: 20011653
Pulsed may outperform continuous wave for brain tissue
Ando et al. (2011) found that 10 Hz pulsed laser was more effective than continuous-wave laser for traumatic brain injury outcomes in a preclinical model — evidence that pulsing frequency itself may influence therapeutic effect beyond simple energy delivery.
PMID: 22028832
Super-pulsed device: no thermal effect across all skin types
Grandinetti et al. (2015) tested the Multi-Radiance super-pulsed laser at 10 J, 30 J and 50 J across 42 participants of all skin types and found no significant skin temperature increases at any dose.
PMID: 25987340
Multi-Radiance device: knee pain reduction
Leal-Junior et al. (2014) demonstrated significant pain reduction (p < 0.05) and improved quality of life scores in a randomised controlled trial of 86 patients with knee pain using the Multi-Radiance super-pulsed device.
PMID: 24844921
Multi-Radiance device: post-surgical pain and inflammation
Langella et al. (2018) found that super-pulsed photobiomodulation decreased VAS pain scores and inflammatory markers (TNF-alpha, IL-8) in a randomised controlled trial of patients following hip arthroplasty (p < 0.05).
PMID: 29909435
Research findings describe outcomes in specific study populations under controlled conditions. Individual responses vary. The presence of published research does not guarantee equivalent outcomes for every patient.
Why Adelaide Cold Laser uses super-pulsed technology
This is not an assertion that super-pulsed is “better” or “superior” to Class IV. Both have clinical applications. Our decision to use the our clinical-grade super-pulsed laser is based on three considerations:
1. Parameter matching
The vast majority of the 700-plus randomised controlled trials in photobiomodulation used Class 3B or super-pulsed devices, not Class IV. The World Association for Laser Therapy (WALT) explicitly separates its dosing recommendations for super-pulsed 904 nm from continuous-wave protocols — recognising them as distinct clinical profiles. We chose a device whose parameters align with the largest published evidence base.
2. Safety profile
Our super-pulsed laser is classified as Class 1M — the same safety tier as a laser pointer. No burns. No mandatory eye protection at treatment distances. No dedicated laser room. Published research confirms no significant skin temperature increase at any tested dose across all skin types (Grandinetti 2015, PMID: 25987340). This means a straightforward, comfortable experience for every patient.
3. Dose precision
The biphasic dose response in photobiomodulation means that the therapeutic window matters. Too little energy produces no effect; too much may be inhibitory (Huang 2009, PMID: 20011653). Super-pulsing delivers high photon density during each nanosecond burst while keeping average power within the range where positive outcomes have been most consistently demonstrated.
Our device at a glance
| Device | our clinical-grade super-pulsed laser |
| Laser class | Class 1M |
| Super-pulsed wavelength | 905 nm (GaAs) |
| Additional wavelengths | 455 nm (blue), 660 nm (red), 875 nm (infrared) |
| Peak pulse power | 50,000 mW (50 W) |
| Pulse duration | ~100–200 nanoseconds |
| Static magnetic field | 35 mT |
| Weight | 250 g (cordless) |
| TGA listing | TGA-registered (Class IIa) |
| FDA clearance | 510(k) cleared |
The device is TGA-registered as a Class IIa therapeutic good. It is not “TGA approved” — no therapeutic good is “approved” in Australia; they are listed or registered on the Australian Register of Therapeutic Goods.
Individual treatment outcomes vary. An initial consultation allows us to assess whether cold laser therapy may be appropriate for your specific condition.
Frequently asked questions
What is the difference between cold laser and hot laser?
Cold laser (super-pulsed) delivers very short, high-energy bursts of light that produce no heat in the tissue. The primary mechanism is photochemical — light is absorbed by cells to trigger biological responses. High-power Class IV lasers deliver continuous energy at higher average power, which creates thermal effects in the tissue. Both have clinical applications, but they work through fundamentally different mechanisms. At Adelaide Cold Laser we use a super-pulsed Class 1M device — our super-pulsed laser — which produces no measurable heat.
Is Class IV laser more powerful and therefore better?
More power does not automatically mean better clinical outcomes. The therapeutic effect in photobiomodulation is photochemical — it depends on the right photon density reaching the right cellular targets, not on raw wattage. Published research describes a biphasic dose response: too little energy produces no effect, but too much may actually be inhibitory (Huang 2009, PMID: 20011653). The majority of positive photobiomodulation trials used parameters consistent with lower-power and super-pulsed devices. Power and effectiveness are not the same thing.
Does cold laser therapy hurt?
No. Most patients feel nothing at all during treatment, and some report a mild tingling. There is no heat, no burning, no discomfort. The device can sit directly on your skin for the full treatment without any risk. This is in contrast to Class IV devices, which generate heat and require continuous movement to avoid thermal injury. Your first visit at Adelaide Cold Laser is $99, and we will explain exactly what to expect before treatment begins.
Which type of laser therapy has more research behind it?
The published evidence base for photobiomodulation spans more than 700 randomised controlled trials. The vast majority of these used Class 3B or super-pulsed lasers, not Class IV devices. Class IV laser therapy is a newer clinical application and its dedicated research base is still growing. Both types have published studies, but the depth and breadth of evidence is currently stronger for lower-power and super-pulsed parameters. We chose our device specifically because its parameters match the parameters used in the largest body of published research.
Can I get burned by cold laser therapy?
No. Our super-pulsed laser is classified as Class 1M — the same safety tier as a presentation laser pointer. A published study tested this specific device at multiple doses across all skin types and found no significant skin temperature increase at any dose (Grandinetti 2015, PMID: 25987340). You can hold it stationary on your skin and there is zero burn risk. Class IV devices, by contrast, require continuous movement during treatment to prevent thermal injury.
Why does your device use multiple wavelengths?
Different wavelengths of light reach different tissue depths and interact with different biological targets. Our super-pulsed laser uses four — 455 nm (blue) for superficial tissue, 660 nm (red) for slightly deeper, 875 nm (infrared) for deeper still, and 905 nm (super-pulsed) for the deepest penetration. They are sequenced so each wavelength prepares the optical pathway for the next. Most Class IV devices use only one or two wavelengths.
What does “super-pulsed” mean?
Super-pulsed means the laser fires in extremely short bursts — each lasting roughly 100 to 200 billionths of a second — with long rest periods in between. During each pulse, peak power reaches 50 watts. But because each burst is so brief and the “off” time is so long (duty cycle of about 0.001%), average power stays very low. The simplest way to picture it: a camera flash delivers intense light for an instant without creating heat. A desk lamp left on continuously creates warmth. Super-pulsing is the camera flash approach.
Is one type of laser therapy safer than the other?
Both types are used clinically with established safety protocols. The practical difference is in the precautions required. Class IV lasers require mandatory protective eyewear for both patient and clinician, a dedicated treatment room with door interlocks and warning signage, and continuous device movement during application. Super-pulsed Class 1M devices require none of these — no eyewear, no special room, no movement restrictions, and no burn risk. Both are safe when used according to their protocols, but the margin for error differs.
What device do you use?
The our clinical-grade super-pulsed laser. It is a super-pulsed Class 1M laser that delivers four wavelengths simultaneously (455, 660, 875 and 905 nm) plus a static magnetic field. It weighs 250 grams, is cordless and rechargeable, and is TGA-registered as a Class IIa therapeutic good. It is also FDA 510(k) cleared. Your first consultation at Adelaide Cold Laser is $99 and includes a full assessment to determine whether cold laser therapy may be appropriate for your situation.
How do I know which type of laser my practitioner uses?
Ask directly. The key questions are: What is the laser classification? What is the average power output? Does it require protective eyewear? If they say Class IV, average power above 500 milliwatts, and eyewear is mandatory — that is a high-power thermal laser. If they say Class 1M or Class 3B, lower average power, and no eyewear required — that is a cold laser or low-level laser device. Any reputable practitioner should be able to tell you the device name, classification and key specifications.
Ready to learn more?
Your initial consultation is $99 and includes a full assessment to determine whether cold laser therapy may be appropriate for your situation.
Or call (08) 8297 5277 — 528 Marion Road, Plympton Park
Questions? We’re here to help.
Call us on (08) 8297 5277 or book online — no obligation.
References
- Ando T, Xuan W, Xu T, et al. Comparison of therapeutic effects between pulsed and continuous wave 810-nm wavelength laser irradiation for traumatic brain injury in mice. PLoS One. 2011;6(10):e26212. PMID: 22028832
- Antonialli FC, De Marchi T, Tomazoni SS, et al. Phototherapy in skeletal muscle performance and recovery after exercise: effect of combination of super-pulsed laser and light-emitting diodes. Lasers Med Sci. 2014;29(6):1967-76. PMID: 24942380
- Barbora A, Bohar O, Sivan AA, et al. Higher pulse frequency of near-infrared laser irradiation increases penetration depth for novel biomedical applications. PLoS One. 2021;16(1):e0245350. PMID: 33411831
- Chaki S, Ganesan P, Kim J. Computational analysis of pulsed wave versus continuous wave laser irradiation for deep tissue photobiomodulation therapy. Comput Biol Med. 2025;191:109740. PMID: 40384056
- de Paiva PRV, Casalechi HL, Tomazoni SS, et al. Does the combination of photobiomodulation therapy and static magnetic field improve aerobic capacity? BMC Sports Sci Med Rehabil. 2020;12:23. PMID: 32308987
- Grandinetti V, Miranda EF, Johnson DS, et al. The thermal impact of phototherapy with concurrent super-pulsed lasers and LEDs on human skin. Lasers Med Sci. 2015;30(5):1575-81. PMID: 25987340
- Huang YY, Chen ACH, Carroll JD, et al. Biphasic dose response in low level light therapy. Dose Response. 2009;7(4):358-83. PMID: 20011653
- Huang YY, Sharma SK, Carroll J, et al. Biphasic dose response in low level light therapy — an update. Dose Response. 2011;9(4):602-18. PMID: 22461763
- Kaub L, Schmitz C. More is not more: higher laser irradiance does not necessarily mean better therapeutic penetration depth. Lasers Med Sci. 2023;38(1):159. PMID: 37239026
- Langella LG, Casalechi HL, Tomazoni SS, et al. Photobiomodulation therapy (PBMT) on acute pain and inflammation in patients who underwent total hip arthroplasty. Lasers Med Sci. 2018;33(9):1933-40. PMID: 29909435
- Leal-Junior EC, Johnson DS, Saltmarche AE, et al. Adjunctive use of combination of super-pulsed laser and light-emitting diodes phototherapy on nonspecific knee pain. Lasers Med Sci. 2014;29(6):1839-47. PMID: 24844921
About this page: This page compares photobiomodulation (cold laser therapy, low-level laser therapy, LLLT, PBM) with Class IV high-power laser therapy (HPLT). It covers the super-pulsed laser mechanism used by the our clinical-grade super-pulsed laser device at Adelaide Cold Laser, 528 Marion Road, Plympton Park SA 5038. Topics include cytochrome c oxidase photon absorption, the biphasic dose response (Arndt-Schultz principle), TGA device registration, World Association for Laser Therapy (WALT) dosing guidelines, and gallium arsenide (GaAs) semiconductor technology. Page reviewed by Dr Sam Johnson (Chiropractor).
The information on this page is provided for general educational purposes only and does not constitute medical advice. Cold laser therapy (photobiomodulation) outcomes vary between individuals. The research cited describes findings in specific study populations under controlled conditions and does not guarantee equivalent results for every patient. Neither cold laser therapy nor Class IV laser therapy should be considered a replacement for medical advice from your general practitioner or specialist. If you have a medical condition, please consult your treating healthcare professional before commencing any new therapy. Adelaide Cold Laser uses an TGA-registered device. Individual results may vary.
